Extensively drug resistant tuberculosis (XDR-TB): A potential threat

نویسندگان

  • Anaga Marwar
  • Ivvala Anand Shaker
  • Hemraz Palawan
  • Nanadal
  • M. S. Ranjith
  • GokulShankar
چکیده

Emergence of extensively drug resistant tuberculosis (XDR-TB) has been reported by more than 55 countries. XDR-TB is considered as untreatable and highly fatal disease. In developing countries like India, number of cases of multi-drug resistant tuberculosis (MDR-TB) and XDR-TB are increasing. Emergence of resistance to Isoniazid and Rifampicin, the two most effective and well tolerated agents, coupled with resistance to second line agents pose limited treatment options for XDR-TB. The present minireview provides information about the seriousness of XDR-TB and the drugs available for its treatment. Although considered a fatal disorder, judicious use of combination of drugs, retaining their antimycobacterial activity, can improve the clinical outcome of XDR-TB. Only such an approach can provide some hope for the patients of XDR-TB.

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عنوان ژورنال:

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2010